Dr. Baidya’s interview with Bio Patrika

Figure 1: GPCR behaves like a mailbox that receives
messages from outside the cell and relays them to cell
machinery by signaling.
Figure 2: Conformation of beta-arrestin (βarr) in vasopressin 2 receptor stimulates ERK signaling but a different beta-arrestin conformation in bradykinin 2 receptor is inhibitory to ERK activation but when Bradykinin 2 receptor mutant with a changed code, made similar to vasopressin 2 receptor now induce a conformation in beta-arrestin which again becomes supportive of ERK activation.

“[…] a paradigm-changing contribution to the field to understand beta-arrestin plasticity and related functions better.”



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